Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

Blog Article

one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is an impurity linked to bortezomib, a proteasome inhibitor Utilized in the remedy of several myeloma. Its synthesis or study is very important for guaranteeing the purity and security of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor while in the synthesis of abiraterone acetate, a drug used in the treatment of prostate most cancers by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-ten-1): A key compound from the synthesis of imatinib, a drug that targets certain varieties of most cancers, which includes Serious myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats many cancers for example breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): They're intermediates during the synthesis of gemcitabine, an anti-cancer drug. Their review is very important for optimizing the output process and guaranteeing higher purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is used to treat breast cancer, and these intermediates are involved with its production.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist Employed in the treatment of breast cancer. A variety of intermediates assist in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-sixteen-9): This intermediate is used in CAS NO. 302964-08-5 the synthesis of paclitaxel, a chemotherapy drug productive in managing cancers such as ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the treatment method of colorectal most cancers and compact mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is involved with the synthesis of adamantane derivatives, that have many purposes, including antiviral Qualities.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for kind 2 diabetes that inhibits the enzyme DPP-four to control blood FULVESTRANT INTERMEDIATES--4(N-4) sugar concentrations.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is associated with the synthesis of various gluconic acid derivatives, which can be used in meals, pharmaceutical, and industrial applications.
Canagliflozin Intermediate two: A precursor during the synthesis of canagliflozin, a medication made use of to deal with form two diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).